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spud100 Profile
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Registered: 12-2017
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Re: The Jury is In - Hydroxychloroquine + Zinc, Used Early, Works


Here is the only thing I have found that coresponds is this, no study has emerged from the chat on Aus tv.

https://i.kym-cdn.com/photos/images/original/001/634/620/24f.jpg
9/18/2020, 12:05 pm Link to this post PM spud100 Blog
 
Tombstone1881 Profile
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Re: The Jury is In - Hydroxychloroquine + Zinc, Used Early, Works


Video falsely touts hydroxychloroquine as COVID-19 cure


CLAIM: A video makes numerous claims about preventing the coronavirus, stating that hydroxychloroquine can prevent and cure COVID-19, and wearing masks and keeping people locked down have no value.

AP’S ASSESSMENT: The video contains a wide range of false information, much of which has been knocked down multiple times by doctors and researchers who study the coronavirus.

THE FACTS: The video, which features a group that calls itself America’s Frontline Doctors, tells viewers they have been duped into isolating themselves to control the virus and encourages people in the U.S. to return to their normal activities. It relies on unsubstantiated and false information to make the case.

The video was viewed millions of times and was retweeted by President Donald Trump. Multiple social media platforms removed the video because it contained false information.

Some of the key claims come from Dr. Stella Immanuel, a Houston physician, who says she has successfully treated 350 patients using the anti-malarial drug hydroxychloroquine. She recommends using it alone as a preventive, and with zinc and azithromycin as a cure for COVID-19.

“I came here to Washington, D.C., to tell America nobody needs to get sick,” she said in the video. “This virus has a cure. It is called hydroxychloroquine, zinc, and Zithromax. I know you people want to talk about a mask. Hello? You don’t need mask. There is a cure. I know they don’t want to open schools. No, you don’t need people to be locked down. There is prevention and there is a cure.”

Claims that hydroxychloroquine is effective in treating the coronavirus have been widely debunked by top health officials and the drug has been a part of several national studies.

The majority of evidence has shown that the drug does not prove to be an effective treatment.

“There is no evidence done in a rigorous study that shows hydroxychloroquine in combination with azithromycin or zinc or whatever combination you use that has any benefit in the treatment of coronavirus to date,”
said Dr. Amesh Adalja, a senior scholar who specializes in infectious diseases at the Johns Hopkins Bloomberg School of Public Health.

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Why is it that not one of the Republican officeholders objecting to Biden's victory have objected to their own wins on the same day on the same ballots using the same election systems??!
9/18/2020, 1:05 pm Link to this post PM Tombstone1881
 
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Re: The Jury is In - Hydroxychloroquine + Zinc, Used Early, Works


Does zinc supplementation enhance the clinical efficacy of chloroquine/hydroxychloroquine to win today's battle against COVID-19?


Currently, there are no approved vaccines or pharmaceutical therapies available for prevention of SARS-CoV-2 infection or treatment of COVID-19. Extensive global research efforts are underway to identify specific vaccination strategies and pharmaceutical targets. However, the development of a specific vaccine is not expected for at least 12–18 months due to required time for research, evaluation, and regulatory approval.
Worldwide, social distancing and self-quarantine are currently the only protective measures to slow the rate of SARS-CoV-2 infections and help to keep the novel coronavirus from overwhelming the healthcare systems. Nevertheless, every day COVID-19 related deaths are still increasing and so the repurposing of available and approved drugs has emerged as a feasible strategy for treatment near term. In this regard, potentially suitable antiviral and immunomodulatory candidates have been identified and selected.

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Why is it that not one of the Republican officeholders objecting to Biden's victory have objected to their own wins on the same day on the same ballots using the same election systems??!
9/18/2020, 1:11 pm Link to this post PM Tombstone1881
 
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Re: The Jury is In - Hydroxychloroquine + Zinc, Used Early, Works


Largest Study To Date Finds Hydroxychloroquine Doesn't Help Coronavirus Patients


A new hydroxychloroquine study -- "the largest to date" -- was published Thursday in the prestigious New England Journal of Medicine. It concluded that Covid-19 patients taking the drug "do not fare better than those not receiving the drug," reports Time:

Dr. Neil Schluger, chief of the division of pulmonary, allergy and critical care medicine at Columbia, and his team studied more than 1,300 patients admitted to New York-Presbyterian Hospital-Columbia University Irving Medical Center for COVID-19. Some received hydroxychloroquine on an off-label basis, a practice that allows doctors to prescribe a drug that has been approved for one disease to treat another — in this case, COVID-19. About 60% of the patients received hydroxychloroquine for about five days.

They did not show any lower rate of needing ventilators or a lower risk of dying during the study period compared to people not getting the drug.

"We don't think at this point, given the totality of evidence, that it is reasonable to routinely give this drug to patients," says Schluger. "We don't see the rationale for doing that." While the study did not randomly assign people to receive the drug or placebo and compare their outcomes, the large number of patients involved suggests the findings are solid. Based on the results, Schluger says doctors at his hospital have already changed their advice about using hydroxychloroquine to treat COVID-19. "Our guidance early on had suggested giving hydroxychloroquine to hospitalized patients, and we updated that guidance to remove that suggestion," he says.


In another study conducted at U.S. veterans hospitals where severely ill patients were given hydroxychloroquine, "the drug was found to be of no use against the disease and potentially harmful when given in high doses," reports the Chicago Tribune.

They also report that to firmly establish whether the drug has any effect, the Bill and Melinda Gates Foundation is now funding a randomized, controlled trial at six medical institutions of hundreds of people who've tested positive for Covid-19.

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Why is it that not one of the Republican officeholders objecting to Biden's victory have objected to their own wins on the same day on the same ballots using the same election systems??!
9/18/2020, 1:15 pm Link to this post PM Tombstone1881
 
greendocnowciv Profile
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Registered: 11-2017
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Re: The Jury is In - Hydroxychloroquine + Zinc, Used Early, Works


That "frontline" vid may be the one Spud wants to see. Thanks, Tomb!

And the idea that no-one has used a study to show this doesn't refute a review of studies, which is what a "meta study" is. Thus, that post is like posting that somebody didn't produce a documented sign from Heaven that the Trump Pills work.

Neither is needed, if one has a valid meta study, of course.

9/18/2020, 1:21 pm Link to this post PM greendocnowciv Blog
 
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Re: The Jury is In - Hydroxychloroquine + Zinc, Used Early, Works


In Viral Video, Doctor Falsely Touts Hydroxychloroquine as COVID-19 ‘Cure’


A video pushing the use of an unproven COVID-19 treatment has received widespread attention, including on Twitter by President Donald Trump and Donald Trump Jr., whose account was temporarily suspended for directly sharing the video.

Twitter, YouTube and Facebook have been removing the video since it started circulating on July 27 and amassing millions of views. The video spreads the debunked claim that COVID-19 can be cured with hydroxychloroquine — the drug that has been continuously touted by the president.

The clip features a Houston-area doctor named Stella Immanuel wearing a white coat in front of the U.S. Supreme Court building as she proclaims that a cocktail of hydroxychloroquine, zinc and the antibiotic azithromycin has cured COVID-19 patients.

Immanuel was speaking at a press conference arranged by an organization called “America’s Frontline Doctors.” We couldn’t find much information about the group and neither its founder, Simone Gold, nor its lawyer, Steven Mitby, returned our calls for comment. But the group appears to be connected to the Tea Party Patriots Foundation, which runs the conservative Tea Party movement. The group’s logo and an open letter to Trump written by Gold are featured on a webpage copyrighted by the foundation.

However, in April, as the COVID-19 pandemic spread across the U.S., Gold stood outside the Cedars-Sinai Medical Center in Los Angeles wearing a white coat embroidered with her name above the words “Emergency Dept.” and recorded videos about her “experience practicing emergency medicine in this era of the COVID-19 crisis.”

In one video she claimed “the emergency department volume is down.” In another video in front of the hospital, she reported that, “we have been very successful at flattening the curve.”

But Gold has never worked at the hospital. In fact, the only time she was affiliated in any way with Cedars-Sinai was when she worked on a per-diem basis in a Cedars-Sinai Medical Network urgent care clinic for less than three weeks in 2015, Sally Stewart, a spokeswoman for Cedars-Sinai told FactCheck.org in an email.

Immanuel is a licensed doctor in Texas and lists her practice as the Rehoboth Medical Center. That medical center is listed as being registered with the Texas Comptroller of Public Accounts in September 2019 by Solange Gabice. We reached Gabice by phone, but she hung up when we asked if her clinic was treating COVID-19 patients with hydroxychloroquine.

It’s worth noting also that the same strip mall in Katy, Texas, that houses the clinic also houses Fire Power Ministries, a Christian ministry run by Immanuel.

When a reporter asked him about Immanuel, who also has claimed that doctors make medicine using DNA from aliens, Trump noted that she appeared with several other doctors.

Hydroxychloroquine Not a COVID-19 ‘Cure’

In the video, Immanuel repeats the word “cure” a half-dozen times when referring to using hydroxychloroquine to treat COVID-19, saying it can prevent any COVID-19 deaths.

“Nobody needs to get sick. This virus has a cure,” she says at one point. “It is called hydroxychloroquine, zinc and Zithromax.” (Zithromax is a brand name for the drug azithromycin.)

First of all, there is no known “cure” for COVID-19, as the Centers for Disease Control and Prevention points out. And the current scientific evidence doesn’t support the conclusion that hydroxychloroquine is effective in treating the disease, as we’ve explained before.

Since early in the novel coronavirus pandemic, hydroxychloroquine — a drug that is used to treat malaria and other illnesses — has been touted as a potential treatment. Trump has repeatedly cited it, at one point referring to it as a “game changer.”

But numerous randomized controlled studies have cast serious doubt on its effectiveness when it comes to COVID-19.

“There are no data from randomized clinical trials that demonstrate effectiveness of hydroxychloroquine for COVID,” Dr. Neil Schluger, chairman of the department of medicine at New York Medical College School of Medicine, told us in a phone interview. Schluger has studied hydroxychloroquine in relation to COVID-19. “There are now several randomized clinical trials that show that it had no effect.”

“The vast majority of expert opinions … is that hydroxychloroquine has no benefit in COVID illness,” he added.

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, also said the drug is “not effective” for treating COVID-19 in a July 28 interview on ABC’s “Good Morning America.”

“The overwhelming prevailing clinical trials that have looked at the efficacy of hydroxychloroquine have indicated that it is not effective in coronavirus disease,” Fauci said.

Amid growing evidence the drug is not effective, the FDA announced in June that it had revoked the EUA for the drugs because they are “unlikely to be effective in treating COVID-19 for the authorized uses in the EUA,” and that the “known and potential benefits” of the drugs “no longer outweigh” the risks — which can include “serious cardiac adverse events and other potential serious side effects.”

A large randomized controlled study called RECOVERY, in the U.K., reported in a preprint, which hasn’t been peer-reviewed, that hydroxychloroquine wasn’t associated with reduced mortality — and was actually associated with “an increased length of hospital stay and increased risk of progressing to invasive mechanical ventilation or death.” The study said that 26.8% of the 1,561 patients given hydroxychloroquine died within 28 days, whereas 25% of patients given usual care died in that time span — a difference that was not statistically significant.

The authors wrote that “these results indicate that hydroxychloroquine is not an effective treatment for patients hospitalized with COVID-19.”

Another study published July 16 in the Annals of Internal Medicine — a randomized, double-blind, placebo-controlled trial that involved more than 400 participants — found that “[h]ydroxychloroquine did not substantially reduce symptom severity in outpatients with early, mild COVID-19.”

There was one observational study by the Henry Ford Health System, published in the International Journal of Infectious Diseases on July 1, that found hydroxychloroquine was associated with lower mortality for patients hospitalized with COVID-19. But, as we’ve explained before, the study has limitations — and it stands in contrast to multiple randomized controlled trials that have found the drug is not beneficial to hospitalized patients (and two other observational studies).

During the press conference, Immanuel also claimed that a 2005 study “said it works.”

That study — which found that “[c]hloroquine is effective in preventing the spread of SARS-CoV in cell culture” — “is no evidence at all that it’s a cure for COVID,” Schluger said.

“That was a different coronavirus; that was the coronavirus that causes SARS,” he said. Secondly, he said, the study involved cells in test tubes. Potential drugs are evaluated in test tubes, then in animals, before they move into the three phases of clinical human trials, he said — and 90% of drug candidates that make it to human trials fail because they aren’t effective or aren’t safe.

A study in a test tube involving a different virus, Schluger added, is “not how the FDA approves drugs.”

Likewise, Dr. Radha Rajasingham, an assistant professor of medicine in the division of infectious diseases and international medicine at the University of Minnesota, told us in an email that “[w]hen something ‘works’ in cell culture, the next step is to test it in animals, and then in humans to prove efficacy in this setting. Thus, it’s not reasonable to make clinical decisions based on one lab-based study.”

Despite the evidence that hydroxychloroquine isn’t an effective treatment for COVID-19, Immanuel in the video generally dismisses such studies (erroneously suggesting that they only involved “20 people, 40 people”) — and claims she has successfully treated more than 350 patients.

She also says: “I’ve put myself, my staff and many doctors that I know on hydroxychloroquine for prevention. Because by the very mechanism of action, it works early and as a prophylaxis.”

There are scientists exploring the use of hydroxychloroquine as a prophylaxis, or preventive, and some results have been published.

Rajasingham and fellow researchers at the University of Minnesota published the results of a post-exposure prophylaxis randomized controlled trial of hydroxychloroquine for COVID-19 in the New England Journal of Medicine on June 3.

The double-blind trial recruited more than 800 volunteers who received either hydroxychloroquine or a placebo within four days of exposure to someone with confirmed COVID-19. Nearly 12% of hydroxychloroquine participants developed a COVID-19-like illness compared with 14.3% of those getting the placebo — a difference that was not significant.

“But without clear evidence that this works in randomized clinical trials (in humans) I would not believe this medicine is efficacious,” she said.

Schluger said he understands why the public is desperate for an answer, and why some might look to hydroxychloroquine. But “the job of doctors and scientists is to figure out if things really work — and as far as we can tell, hydroxychloroquine doesn’t seem to have any significant effect.”

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Why is it that not one of the Republican officeholders objecting to Biden's victory have objected to their own wins on the same day on the same ballots using the same election systems??!
9/18/2020, 1:30 pm Link to this post PM Tombstone1881
 
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Re: The Jury is In - Hydroxychloroquine + Zinc, Used Early, Works


How false hope spread about hydroxychloroquine to treat covid-19 — and the consequences that followed


Even before Trump started talking about the drugs, studies abroad sparked interest in them as a potential cure. News about the drugs spread quickly online, percolated to the media and the White House.

Scientists have since pointed to major flaws in those original studies and say there is a lack of reliable data on the drugs. Experts warn about the dangerous consequences of over-promoting a drug with unknown efficacy: Shortages of hydroxychloroquine have already occurred, depriving lupus and rheumatoid arthritis patients of access to it. Doctors say some patients could die of side effects. Other potential treatments for covid-19 could get overlooked with so much concentration on one option.

The Fact Checker video team has reconstructed how the claim spread online and illustrates the troubling consequences of such misleading hope in the drugs.

The Facts
Conversation around hydroxychloroquine and chloroquine as potential treatments for covid-19 started in China in late January. According to Kate Starbird of the University of Washington’s Center for an Informed Public, tweets from media organizations — including Chinese state outlets — and investors highlighted past studies in which the medications were tested as cures for severe acute respiratory syndrome. (The 2005 tests never made it to human trials.) They also pointed to statements from the coronavirus research center in Wuhan, China, suggesting the drugs could be used to fight covid-19.

Renée DiResta, technical research manager at the Stanford Internet Observatory, found similar trends on Facebook and Instagram in February. The number of total posts and interactions increased, and Internet speculation spread beyond China to Nigeria, Vietnam and France.

A large portion of activity online at the end of February and early March appeared in French and centered on a study published by French researcher and doctor Didier Raoult.

The spread in the U.S.

Raoult’s findings helped bring the theory to the United States. However, scientists have since discredited the trial, pointing to major flaws in the way it was conducted. The journal that published the study announced on April 3 that it did not meet its standards.

Yet before the record could be set straight, the hypothesis spread widely on U.S. social media. The Fact Checker has refrained from linking to original posts on the drugs to avoid giving further oxygen to misleading information.

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Why is it that not one of the Republican officeholders objecting to Biden's victory have objected to their own wins on the same day on the same ballots using the same election systems??!
9/18/2020, 1:35 pm Link to this post PM Tombstone1881
 
greendocnowciv Profile
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Re: The Jury is In - Hydroxychloroquine + Zinc, Used Early, Works


This-here Gateway Pundit article refers to a multivariant study, and describes it a little:

https://www.thegatewaypundit.com/2020/07/despite-media-lies-study-shows-hydroxychloroquine-can-provide-50-70-chance-recovery-china-coronavirus/

So that may be the study that Scott Adams was discussing. The article also has other good Hyrdo news from one of the Doctors who was in New York, treating so many victims they had.

9/18/2020, 1:45 pm Link to this post PM greendocnowciv Blog
 


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